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Postdoctoral Researcher / Bioinformatician (f/m/x)

Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)
locationBonn, Deutschland
VeröffentlichtVeröffentlicht: 18.5.2026

Using deep (endo)phenotypic data obtained in the context of both population-based and clinical cohort studies, we aim to identify the risk factors, causes, as well as trait and state markers of neurodegenerative diseases through application of epidemiological and bioinformatics approaches.

The group's main focus is on the assessment of the role of genomic instability, somatic mutations, and retrotransposable elements in the pathogenesis of neurodegenerative diseases. Supported by a technician, the candidate will be responsible for coordinating high-throughput bio-sample selection and preparation, design of probes and libraries for deep targeted next-generation DNA sequencing, as well as bioinformatic analysis of the resulting data, including development of novel methods for assessing genomic instability and somatic mutations.

The team

You will work in a large international team of scientists within the section of Population Health Sciences of the German Centre for Neurodegenerative Diseases. The team members have diverse backgrounds, ranging from epidemiology, psychology, biology, and medicine to bioinformatics and machine learning. In addition, you will have ample opportunity to interact and collaborate with many other scientists (including other bioinformaticians) working at the German Center for Neurodegenerative Diseases and the University of Bonn.

Postdoctoral Researcher / Bioinformatician (f/m/x)
Code: 1535/2026/4

full time, extension possible.
Location: Bonn


Aufgaben

We are looking for a highly motivated postdoctoral researcher / bioinformatician (f/m/x) to join our research group “Population & Clinical Neuroepidemiology” in the group of Prof. Dr. Dr. Ahmad Aziz in Bonn.

  • Supervision of acquisition and processing of data (including genotyping arrays, DNA / RNA sequencing and proteomic data)
  • Supervision of graduate and PhD students
  • Analysis of next-generation (long-read) sequencing data, including development of novel bio-informatic methods focused on assessing genomic instability and somatic mutations
  • Writing and preparation of manuscripts for publication in peer-reviewed journals
  • Maintaining contact with our internal and external academic and industrial partners
  • Preparation of grant applications

Profil
  • Highly talented, motivated, and ambitious researcher with strong social skills
  • PhD in computational biology, molecular biology, (bio)medical sciences, or a related discipline
  • Extensive experience in bioinformatics and large-scale multi-omics projects, particularly in genomics and transcriptomics
  • Demonstrated interest in quantitative research
  • Strong analytical skills
  • Ability to think independently and critically
  • Leadership capabilities
  • Excellent communication and writing skills in English
  • Proficiency in German is desirable

Wir bieten
  • Innovation and internationality – a forward-looking infrastructure, modern laboratory and office equipment, software tools, and the opportunity for international exchange with your colleagues from 65 nations

  • Focus on development – training programs tailored to your individual needs and annual HR development meetings for concrete prospects and potential development

  • Health promotion – through our extensive range of company health programs in cooperation with Sozialwerk.Bund

  • Work-life balance – we reconcile work and private life with flexible working hours, 30 days' holiday (on top free on Christmas Eve and New Year's Eve) and subsidized job / Germany ticket options

  • A feel-good working environment – our Bonn employees enjoy a campus surrounded by greenery, with on-site parking and public transport connections as well as our company restaurant

  • Remuneration and conditions according to TVöD-Bund – including annual special payment, capital-forming benefits, and VBL supplementary pension scheme


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